Buy Semaglutide for Research

Core Research Peptides stocks Semaglutide 5mg as a lyophilized research powder, held in the United States and dispatched the same day on orders placed before 4PM ET. One vial is $99.00, and published bundle pricing lowers the per-vial price at two, three and five units.

What researchers look for in a Semaglutide supplier

Semaglutide is the single most studied GLP-1 receptor agonist in the literature, which makes it the default comparator in almost every incretin experiment. It is also the compound the widest range of sellers list, and most of them are forwarding inventory they have never held, on a timeline they do not control. Four things separate a supplier a lab can plan around from one it cannot.

Material that is already in the country. A peptide sitting in an overseas queue is not inventory, it is a promise. Every Semaglutide vial we sell is in a US facility before it goes on the shelf, so the stock number on the product page is a real count and the ship date does not depend on a customs window.

A purity standard that is stated, not implied. Core Research Peptides buys to a 99% or higher purity standard across the catalog, and Semaglutide 5mg is held to it. Material that does not meet the standard does not get listed. When a comparator compound drifts, every arm of the experiment moves with it, so this is the last place to accept a vague answer.

Pricing you can read without asking for it. Volume pricing normally lives behind an email thread. Ours is printed on the product page: 5% off the per-vial price at two units, 10% at three, 15% at five, floored to whole dollars, and applied in the cart with no code to hunt for.

A checkout that finishes and a person who answers. You pay with a normal Visa or Mastercard on the site and the order is done in one pass. When something needs a human, support replies within one business day.

Product details

Compound: Semaglutide, a GLP-1 receptor agonist
Presentation: 5mg lyophilized powder in a sealed vial
SKU: CRP-SEM-5
CAS number: 910463-68-2
Purity standard: 99% or higher
Price: $99.00 per vial, with bundle pricing at two, three and five units
Availability: in stock, ships from the United States
Supplied for: laboratory research use only

Semaglutide 5mg, in stock and ready to ship today

Buy Semaglutide 5mg Browse the catalog

$99.00 per vial. Free shipping over $150. Same-day dispatch before 4PM ET, seven days a week.

What Semaglutide is, in research terms

Semaglutide is a synthetic 31 amino acid analog of human GLP-1, CAS 910463-68-2. Three engineered changes define it. An alpha-aminoisobutyric acid substitution at position 8 blocks DPP-4 cleavage, a substitution at position 34 removes a competing acylation site, and a fatty diacid attached through a spacer at lysine 26 gives strong albumin binding. The result is a GLP-1 receptor agonist stable enough to hold a steady exposure across a long study window, which is exactly what a comparator compound needs to be.

That stability is why Semaglutide became the reference molecule. In receptor work it gives a clean, selective GLP-1 receptor signal with no GIP receptor component, so it defines the baseline that dual agonists are measured against. Investigators use it to separate GLP-1 receptor driven cAMP accumulation, beta-cell insulin secretion and glucagon suppression from anything a second receptor arm contributes.

The published literature spans glucose homeostasis and insulin secretion work, GLP-1 receptor binding and signaling assays in pancreatic, gastrointestinal and neural tissue, metabolic and energy expenditure studies in animal models, cardiovascular and endothelial models, and neuroendocrine signaling. Our Semaglutide research overview collects the structural detail and the study landscape in one place. This page covers buying the material.

Labs comparing selective and dual incretin pharmacology run this compound next to Tirzepatide 10mg, which engages both the GLP-1 and GIP receptors. We stock both, so a paired order ships together.

Bundle pricing, printed on the page

Quantity	Per vial	Order total	Savings
1 vial	$99	$99	–
2 vials	$94	$188	$10
3 vials	$89	$267	$30
5 vials	$84	$420	$75

The tiers are 5%, 10% and 15% off the single-vial price, floored to whole dollars, and the cart applies them automatically. No code, no account tier, no negotiation. A two-vial order clears the $150 free shipping threshold on its own, so the real cost of the second vial is $94 less the $12 you would otherwise spend on Standard Shipping. Because Semaglutide is usually the control arm rather than the variable, most groups buy it three or five vials at a time and keep one comparator lot running across a whole series.

US stock and same-day dispatch

Orders placed before 4PM ET are dispatched the same day, seven days a week. Seven, not five. A Saturday morning order goes out Saturday, which takes two days off the arrival window against any supplier that batches shipments on weekdays only. Tracking is emailed the same day the parcel leaves.

Shipping is free on every order over $150, which the two-vial Semaglutide bundle already clears. Below that, Standard Shipping is $12. Expedited 2-3 Day and Overnight are both offered at checkout when a run is scheduled and the material has to be on the bench by a fixed date.

Storage and handling

Semaglutide arrives lyophilized and sealed, and that is the state to keep it in until the day it is used. Store the sealed vial dry, cool and away from light. Once reconstituted, refrigerate at 2 to 8 C, keep it light protected, and date the vial. Lyophilized peptide is far more forgiving than peptide in solution, so it is worth reconstituting what a run actually needs instead of the whole vial at once. That matters more for a control compound than for anything else on the bench, because a drifting comparator quietly moves every result you compare against it. Full guidance is on our storage and handling page, and the reconstitution calculator does the arithmetic for you.

Checkout, payment and support

Checkout takes Visa and Mastercard directly on the site. The order is placed and confirmed in one pass, with an email confirmation immediately and tracking as soon as the parcel is scanned. There is no quote step, no invoice to wait on, and no payment link sent hours later while the stock you wanted goes to someone else.

Support answers within one business day. If a vial arrives damaged or an order is not what was ordered, send a photo within 48 hours and we replace it. That is the whole process.

Order Semaglutide 5mg

Semaglutide 5mg is in stock at $99.00 per vial, held in the United States, with bundle pricing at two, three and five units and same-day dispatch before 4PM ET.

Ready when you are

Buy Semaglutide 5mg Compare with Tirzepatide

99% or higher purity standard. Visa and Mastercard accepted. Support replies within one business day.

Frequently asked questions

What is Semaglutide?

Semaglutide is a synthetic 31 amino acid analog of human GLP-1 that acts as a selective GLP-1 receptor agonist, CAS 910463-68-2. Core Research Peptides supplies it as a 5mg lyophilized powder in a sealed vial, for laboratory research use only. It is not for human consumption.

Why buy Semaglutide from Core Research Peptides?

The material is held in stock in the United States, orders placed before 4PM ET are dispatched the same day seven days a week, bundle pricing is published on the product page instead of quoted on request, and checkout takes a normal Visa or Mastercard payment. Support replies within one business day.

What purity is your Semaglutide?

Core Research Peptides holds a purity standard of 99% or higher on every research peptide it stocks, and Semaglutide 5mg is held to that standard. Material below it is not listed.

How fast do you ship Semaglutide, and what does shipping cost?

Orders placed before 4PM ET are dispatched the same day, seven days a week, and tracking is emailed the same day the parcel leaves. Shipping is free on orders over $150, which a two-vial Semaglutide bundle already clears. Below that, Standard Shipping is $12, Expedited 2-3 Day is $39, and Overnight is $95. International shipping is available: Standard International is $40 flat in 10 to 20 business days, free on orders of $500 and above, and Express International is $100 flat in 5 to 10 business days.

What payment methods do you accept?

Checkout takes Visa and Mastercard directly on the site, so an order is placed and confirmed in one pass. There is no quote step and no waiting on an invoice before the order is picked. Bitcoin, Zelle, Cash App and Venmo are also accepted at checkout.

Do you offer bundle pricing on Semaglutide?

Yes. Two vials are $94 each for a $188 total, three vials are $89 each for $267, and five vials are $84 each for $420. The tiers are 5%, 10% and 15% off the single-vial price, floored to whole dollars, and the cart applies them automatically with no code.

How should Semaglutide be stored?

Keep the sealed lyophilized vial dry, cool and away from light. Once reconstituted, refrigerate at 2 to 8 C and keep it protected from light. Full guidance is on the Core Research Peptides storage and handling page.