Core Research Peptides stocks TB-500 5mg as a 5mg vial of lyophilized powder, held in the United States at $75 per vial. Bundle pricing lowers the per-vial price automatically at two, three and five units, with no code to enter. Orders placed before 4PM ET are dispatched the same day, seven days a week, and tracking is emailed the same day.
What researchers look for in a TB-500 supplier
Sourcing TB-500 is a supply problem before it is a chemistry problem. A 43 residue peptide is a long solid-phase synthesis, so batch sizes are finite and lead times move when a run slips. What separates suppliers is whether the vial is already on the shelf, whether the price is printed on the page, and whether the parcel moves the day the order lands.
Stock that is physically here. TB-500 5mg is held in the United States, not routed from a broker overseas after the order lands. The product page shows 9 vials in stock and that count is real. A listing at zero comes down rather than taking orders it cannot fill.
Published pricing, no quote process. One vial is $75. Two are $71 each, three are $67 each, five are $63 each. Those numbers sit on the page before anything goes into a cart, and the bundle discount applies itself. No minimum order, no account, no email exchange to reach a price.
Same-day dispatch, seven days a week. An order placed before 4PM ET leaves the same day, and the tracking number is emailed the same day rather than the next morning. Because the TB-500 vials sit on a shelf in the United States, the cutoff holds on a Saturday as well as on a Tuesday.
Purity held to one standard. TB-500 is held to the same purity standard as the rest of the catalog, and material that does not meet it is not listed. Every vial ships as a lyophilized powder with a 5mg fill under SKU CRP-TB5-5.
Product details
- Compound: TB-500 – Thymosin Beta-4 Synthetic Analog (43 aa)
- Presentation: 5mg lyophilized powder in a sealed vial
- SKU: CRP-TB5-5
- CAS number: 77591-33-4
- Molecular weight: 4,963.44 Da
- Price: $75.00 per vial, with bundle pricing at two, three and five units
- Availability: in stock, ships from the United States
- Supplied for: laboratory research use only
TB-500 5mg, $75 per vial, in stock and shipping today.
Buy TB-500 5mgBrowse the catalogDispatched same day on orders placed before 4PM ET, seven days a week. Standard Shipping is $12, free over $150.
What TB-500 is, in research terms
TB-500 is a synthetic 43 amino acid peptide based on thymosin beta-4, an actin-binding protein present across mammalian tissues. It carries the molecular formula C212H350N56O78S, a molecular weight of 4,963.44 Da and CAS number 77591-33-4. The functional feature of the sequence is the LKKTETQ heptapeptide, the short internal motif that contacts globular actin. The peptide ships as a lyophilized powder in a 5mg vial and dissolves readily in bacteriostatic water for a concentration series.
As a tool compound it isolates a single variable. Published preclinical work uses it to shift the balance between globular and filamentous actin in a culture and then read out what changes, which separates cytoskeletal effects from receptor driven signaling. The full length 43 amino acid analog also enables a direct comparison against the isolated LKKTETQ fragment, so an experiment can test whether the core motif reproduces an effect on its own.
The published literature runs in cell culture and small animal models. Common systems include human umbilical vein endothelial cells, dermal fibroblasts, keratinocytes and corneal epithelial monolayers, together with rodent models of dermal injury, corneal injury and cardiac ischemia. The assay classes are pyrene-actin polymerization, scratch and transwell migration, tube formation on basement membrane extract, immunostaining for actin and endothelial markers, and qPCR expression panels. TB-500 (Thymosin Beta-4) Research Overview walks through those model systems in more detail.
free research guide for TB-500 covers the reconstitution arithmetic for the 5mg vial, storage temperatures for both the sealed and the reconstituted form, handling practice at the bench, and the assay classes above. It is free, it needs no account, and it downloads as a PDF.
Bundle pricing, printed on the page
| Quantity | Per vial | Order total | Savings |
|---|---|---|---|
| 1 vial | $75 | $75 | – |
| 2 vials | $71 | $142 | $8 |
| 3 vials | $67 | $201 | $24 |
| 5 vials | $63 | $315 | $60 |
Actin work spreads across cell types by design. Pyrene actin polymerization, scratch and transwell migration, and tube formation on basement membrane extract rarely share a single vial, and running the full 43 residue peptide against the isolated LKKTETQ motif doubles every one of those arms. At three vials the order crosses $150 and US shipping is included. Quantity does the pricing here: 5% off per vial for two, 10% for three, 15% for five, with the cart doing the arithmetic.
US stock, international shipping and same-day dispatch
Orders placed before 4PM ET are dispatched the same day, seven days a week, weekends included. Tracking is emailed the same day the parcel leaves, so no order sits paid for and silent. Stock is held in the United States, which is why the promise holds on a Saturday. Nothing waits on a supplier in another time zone.
Inside the United States, Standard Shipping is $12 and arrives in 2 to 5 business days, free on orders over $150. Expedited 2-3 Day is $39. Overnight is $95. Standard International is $40 flat at 10 to 20 business days, free on orders of $500 and above, and Express International is $100 flat at 5 to 10 business days.
Storage and handling
The sealed lyophilized vial holds at minus 20C for long-term storage and tolerates 2 to 8C for short periods, which covers transit and staging in a working refrigerator. Once bacteriostatic water is added, hold the solution at 2 to 8C, keep it sealed and out of light, and aliquot before freezing rather than thawing the same volume twice. storage and handling page sets out the full temperature guidance, and reconstitution calculator works out the concentration for any diluent volume.
Checkout, payment and support
Checkout takes Visa and Mastercard directly on the site, in one pass. There is no redirect to a third-party wallet, no invoice to wait on and no phone call. Bitcoin, Zelle, Cash App and Venmo are also accepted at checkout. Card details are entered once and the confirmation email arrives with the order number on it.
Support replies within one business day. If a parcel arrives damaged, or the vials inside do not match the order, send the order number and photographs and it is replaced or refunded. There is no restocking argument to get through first.
Order TB-500 5mg
TB-500 5mg is $75 per vial, lyophilized, held in the United States, with 9 vials in stock as this page was written. Bundle pricing drops the per-vial price to $71, $67 and $63 at two, three and five units. Order before 4PM ET and it ships today.
Three vials at $67 each, and shipping is free.
Buy TB-500 5mgFree TB-500 research guideBundle pricing applies in the cart with no code. Two vials $71 each, three vials $67 each, five vials $63 each.
More buying guides
Every compound in the catalog has one of these pages, with the same published pricing and the same dispatch terms.
Frequently asked questions
What is TB-500?
TB-500 is a synthetic 43 amino acid peptide based on thymosin beta-4, an actin-binding protein found across mammalian tissues. Its molecular formula is C212H350N56O78S, its molecular weight is 4,963.44 Da and its CAS number is 77591-33-4. The functional element of the sequence is the LKKTETQ motif, which binds globular actin. It ships as a lyophilized powder in a 5mg vial, for laboratory research use only.
Why buy TB-500 from Core Research Peptides?
Stock is held in the United States and dispatched the same day on orders placed before 4PM ET, seven days a week, with tracking emailed the same day. Pricing is published on the page: $75 for one vial, $71 each at two, $67 at three and $63 at five, applied automatically in the cart. Card checkout finishes in one pass and support replies within one business day.
What purity is your TB-500?
TB-500 is held to the same purity standard as every other compound in the Core Research Peptides catalog. Material that does not meet that standard is not listed and does not ship. Each vial is a lyophilized powder with a 5mg fill under SKU CRP-TB5-5, supplied for laboratory research use only.
How fast do you ship TB-500, and what does shipping cost?
Same-day dispatch applies to any TB-500 order that lands before 4PM ET, seven days a week, and tracking is emailed the day the parcel leaves. Domestic Standard Shipping costs $12 and takes 2 to 5 business days, and it costs nothing once the order total passes $150. Expedited 2-3 Day is $39 and Overnight is $95. A three vial order of TB-500 totals $201, so it ships Standard at no charge.
Do you ship TB-500 internationally?
Yes. Standard International is a $40 flat rate and arrives in 10 to 20 business days, free on orders of $500 and above. Express International is a $100 flat rate at 5 to 10 business days. International orders leave the same day when they land before 4PM ET. Import rules are the buyer’s responsibility.
Do you offer bundle pricing on TB-500?
Yes. Two vials take 5% off the per-vial price at $71 each, three take 10% off at $67 each, and five take 15% off at $63 each, floored to whole dollars. That is $142, $201 and $315 in total, saving $8, $24 and $60. The discount applies itself in the cart with no code, and a coupon code stacks on top of it.
How should TB-500 be stored?
Store the sealed lyophilized vial at minus 20C for long-term holding, with 2 to 8C acceptable for short periods such as transit. After reconstitution with bacteriostatic water, hold the solution at 2 to 8C, sealed and out of light, and split it into single use aliquots before freezing.
